DIAGNOSTIC VALUE OF MEAN PEROXIDASE INDEX IN EARLY KAWASAKI DISEASE
Authors
Abstract:
The charts of 27 patients with Kawasaki disease (KD) admitted to Nemazee Hospital in Shiraz from January 1991 to October 1998 were reviewed to identify the results of mean peroxidase index (MPXI) values, a measure of neutrophil staining intensity, obtained by the Technicon HI analyzer (Technicon Instruments Corp., Tarrytown, NY) within the first 10 days of the illness 2 separate groups of patients were assessed as control subjects: 27 disease control (DC) children with fever plus one other KD criterion and 27 laboratory control (LC) subjects with nonfebrile disorders interpreting also as a normal reference population. Compared with control groups, patients with KD had lower quantities of MPXI [(Mean±SD, -11.71±5.87 in KD group) vs. (1.53±4.30 p<0.001 in DC group, and 1.74±6.52,p<0.001 in LC group)]. Depending on the location of the cut-off point expressed on an interval scale, this test had the ability to be 100% specific ( if MPXI0). Considering the low prevalence of hereditary myeloperoxidase (MPO) deficiency ( 1 in 2000), measurement of MPXI, when performed as part of a complete count on an automated hematology instrument, could be counted as an important adjunct to clinical evaluation and also according to the low values of MPXI in patients with KD, it can be included among the acquired causes of MPO deficiency.
similar resources
diagnostic value of mean peroxidase index in early kawasaki disease
the charts of 27 patients with kawasaki disease (kd) admitted to nemazee hospital in shiraz from january 1991 to october 1998 were reviewed to identify the results of mean peroxidase index (mpxi) values, a measure of neutrophil staining intensity, obtained by the technicon hi analyzer (technicon instruments corp., tarrytown, ny) within the first 10 days of the illness 2 separate groups of patie...
full textDiagnostic and Prognostic Value of Cardiac Biomarkers in Children with Kawasaki Disease: A State-of-the-Art Review
Kawasaki disease (KD) is characterized as the leading cause of acquired cardiac disease in children. Accurate and timely diagnosis of KD is of high importance for preventing its cardiac complications. However, diagnosis merely based on clinical findings has a number of challenges and, limitations. Therefore, researchers are investigating to find more object...
full textDiagnostic Value of Calretinin and S100 Immunohistochemistry in Hirschsprung's Disease
Background Rectal biopsy and its histopathological study with hematoxylin and eosin (HE) is the gold standard for Hirschsprung's disease (HD) diagnosis. However, there are some limitations in the diagnosis of ganglion cells in HE approach. Recently, it was reported that the utility of Calretinin is a reliable ancillary immunohistochemistry (IHC) test for HD diagn...
full textEarly Detection of Kawasaki Disease in Infants.
BACKGROUND AND OBJECTIVES This study aimed to investigate the clinical characteristics of infantile Kawasaki disease (KD), and to evaluate early diagnostic features of KD in febrile infants. SUBJECTS AND METHODS We retrospectively reviewed the medical records of 64 KD patients from January 2010 to October 2014. There was an analysis of the clinical, laboratory data of the infants versus child...
full textDiagnostic characteristics of supplemental laboratory criteria for incomplete Kawasaki disease in children with complete Kawasaki disease
PURPOSE In 2004, the American Heart Association (AHA) had published an algorithm for the diagnosis of incomplete Kawasaki disease (KD). The aim of the present study was to investigate characteristics of supplemental laboratory criteria in this algorithm. METHODS We retrospectively examined the medical records of 355 patients with KD who were treated with intravenous immunoglobulin (IVIG) duri...
full textMy Resources
Journal title
volume 14 issue 2
pages 107- 110
publication date 2000-08
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023